As much as I love Jon Stewart, Stephen Colbert and Seth MacFarlane, I had to go with relentless stridency. I present the Four Horsemen of Comedy: Ricky Gervais, Jim Jeffries, Doug Stanhope and Bill Maher. Speaking of comedy, how about those New Atheists?
The argument from reasonable nonbelief- If the existence of the gods were self-evident, everyone would believe. The burden of proof is on religion.
Lack of empirical evidence- Discovery trumps revelation. The incorporeal is immaterial.
The argument from inconsistent revelations- All religions can't be right, so they're probably all wrong. Sectarian religions are mutually contradictory, internally inconsistent and incoherent.
The argument from evil- If the gods are real, they have a lot of explaining to do.